Bio-pharmaceuticals refers to the manufacture of products from organisms, biological tissues, cells and body fluids, etc. by comprehensive utilization of the research results, scientific principles and methods of microbiology, biology, medical science, chemistry, biochemistry, biotechnology, pharmacy and so on, for disease prevention, treatment and diagnosis purposes.

China's biopharmaceutical industry is facing a favorable development environment. In recent years, with continuous transformation and upgrading of Chinese domestic biopharmaceutical industry, and with the enhancement of the R&D investment, production capacity and industry concentration, the overall technical level of China's biopharmaceutical industry has been significantly improved, which provides a strong foundation for biopharmaceutical research and development.
 
With the progress of the preliminary stage R&D level of biopharmaceutical industry, higher requirements have been placed on the corresponding time, efficiency and cost of the R&D. In order to invest less in the preliminary stage and have a short R&D time, the research and the production of micro-level raw materials in the preliminary stage need the corresponding high-level extraction equipment for clarification, purification and concentration purposes, which brings difficulties for the development of the industry, especially for some new technologies, such as membrane separation and purification technology, electrodialysis technology and so on.
 
The current membrane separation and purification equipment can not be used in the micro-level product and process R&D in the biopharmaceutical industry. As a result, companies and research institutions have to increase the amount of research products, or are forced to enlarge the amount of research products. If the amount of research product cannot be enlarged during R&D period, it means that new technologies and processes have to be given up. This makes the research of the extraction technology and process in biopharmaceutical industry face an embarrassing situation that whether they have to keep backward or they are unable to utilize certain extraction technology and process.

In terms of membrane separation and purification, if the corresponding membrane equipment can be used for the micro-level product and process R&D, then the difficult problem for preparation of micro-level raw materials for biopharmaceutical industry will be solved, which is also the problem that the relevant enterprises and research institutions are eager to solve. At present, the minimum feed rate of membrane separation equipment on the market is 2L or more. If the feed rate is lower than this, the experimental equipment may be unable to work or the experimental data may not be accurate. However, the raw material amount required by the preliminary R&D stage in biopharmaceutical industry is generally 200ML~1L, or even less, which leads to the problems mentioned above.
 
In order to solve the problem of preparing micro-level raw materials for the preliminary R&D stage in biopharmaceutical industry, Guo Chu Technology (Xiamen) Co., Ltd., based on its advantage and experience, has developed Micro-Scale Tangential-Flow Experimental Device specially for universities, scientific research institutions and enterprise laboratories. The device can work with very little feed amount and the minimum circulation volume is only 50ml, which is mainly used for laboratory experiments for micro-level raw material separation, purification, concentration and extraction, such as: separation and purification of micro-level raw water, cell separation and purification, protein separation and purification, polysaccharide separation and purification, sugar alcohol separation and purification, component concentration desalination, antibiotic separation and purification, anti-tumor drug separation and purification, animal extract separation and purification, plant extract separation and purification, fermentation broth separation and purification, amino acid separation and purification, enzyme separation and purification.
 

 
It is reported that the device has been adopted by many membrane R&D institutions, mainly used for testing the performance of microfiltration membrane, ultrafiltration membrane, nanofiltration membrane, reverse osmosis membrane, modified membrane, or for membrane flux test, membrane rejection rate test, membrane solvent resistance test, membrane alkali resistance test, membrane acid resistance test, membrane temperature resistance test, membrane recovery test after membrane cleaning, membrane anti-pollution test, membrane integrity test and so on.
 
Guo Chu Technology (Xiamen) Co., Ltd. now has strategic cooperation with many global membrane manufacturing giants. It can provide membrane materials with full range of precision covering microfiltration, ultrafiltration, nanofiltration and reverse osmosis, which can achieve selective separation under the condition that the feed liquid amount in the laboratory is very small, which has been regarded as a sharp weapon for the preliminary lab R&D for biopharmaceutical products, which can also realize the function of ‘one machine with multiple purposes’.