Conventional filtration means liquid directly passes through the filter membrane to enter the downstream, while large particles or molecules are trapped in the upstream or inside of the membrane, and small particles or molecules enter the downstream through the membrane under pressure action. The flow direction of the operating cube is perpendicular to the surface of the membrane, so it is also called "dead end filtration". The application of conventional filtration includes clarification and filtration, bacteria removal and filtration, virus filtering and so on.

Cross-flow filtration means that the flow direction of liquid is parallel to the surface of the membrane. Under the action of pressure, only a part of liquid passes through the filter membrane to enter the downstream. This operation mode is called "cross flow filtration".  As tangential flow continues to “scour”the membrane surface in filter process, so it effectively alleviates the accumulation of large particles and molecules on the membrane under this mode of operation, this makes this mode of operation unique in many applications.

In the tangential flow filtration system, the material fluid is not forced to pass through a single path through the membrane as a dead end filtration. Instead, the fluid passes through the membrane surface repeatedly through the way of repeated re-circulation. The "cleaning", brought by pressure, reduces the accumulation of pollutants on the surface of the membrane. The flow of liquid produces shear force on the surface of the filter medium, which reduces the accumulation of the filter cake layer or the gel layer, thus ensuring the stable filtration speed. The target molecules with larger molecular weight than the film are retained, but small molecules and buffer solutions pass through the membrane.

Tangential flow filtration can be used to separate large biomolecules from small biomolecules, capture cell suspensions, and clarify fermentation broth and cell lysate. It can be applied to a series of applications including protein chemistry, molecular biology, immunology, biochemistry and microbiology.

Micro membrane filtration experimental equipment  is a set of micro experimental devices designed by GUOCHU Technology specially for Laboratories in colleges, institutes and enterprises, it is mainly applicable to laboratory small-scale research. The system adopts imported flat membrane, and its molecular weight ranges from micro-filtration, ultra-filtration, nano-filtration and reverse osmosis to the full range of accuracy. It can realize the separation needs of micro-filtration, ultra-filtration, nano-filtration and reverse osmosis under a small amount of liquid in the laboratory.

Features of Micro membrane filtration experimental equipment

•   Simple and practical technology and beautiful appearance
•   Easy to install and easy to maintain
•   The operation of the equipment is convenient and the operation is stable
•   Stainless steel material, corrosion resistance, long equipment life
•   Compact design, small size of equipment and less area covering;
•   The area of filling membrane is small and the amount of material needed is less;
•   Reliable experimental parameters
•   Brand products, quality assurance
•   High pressure equipment is up to 40bar
•   Convenient replacement of diaphragm
•   Complete set of diaphragm, covering the whole range of micro-filtration, ultra-filtration, nano-filtration and reverse osmosis

Typical applications:

•   Teaching demo
•   Separation and purification of trace material
•   Cell separation and purification
•   Protein separation and purification
•   Separation and purification of polysaccharide
•   Separation and purification of sugar alcohol
•   Concentration and desalination of components
•   Isolation and purification of antibiotics
•   Isolation and purification of antitumor drugs
•   Isolation and purification of animal extracts
•   Isolation and purification of plant extracts
•   Separation and purification of fermentation broth
•   Separation and purification of amino acids
•   Isolation and purification of enzyme preparation
•   Performance test of microfiltration membrane
•   Performance test of ultrafiltration membrane
•   Performance test of nanofiltration membrane
•   Performance test of reverse osmosis diaphragm
•   Performance test of seawater desalination diaphragm
•   Performance test of brackish water desalination film
•   Performance test of film modification
•   Membrane flux test
•   Test of film interception rate
•   Solvent resistance test of diaphragm
•   Test of alkali resistance of diaphragm
•   Test of acid resistance of diaphragm
•   Test of temperature resistance of diaphragm
•   Recovery test of diaphragm cleaning
•   Anti pollution test of diaphragm
•   Diaphragm integrity test

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